Endocrine Abstracts

Differentiated thyroid cancer (DTC) in general has a good prognosis when ist diagnosed early. Late stage disease with bone metastasis may cause severe complications, increases mortality rate, decreases the quality of life, and shortens the patients’ survival. The treatment is still controversial. Surgery or radioiodine therapy alone is usually unsatisfactory.Case presentation: We report a case of a 40-year-old female presented, in August 2012, with ...

Aim of the study: Thyroid cancer comprises the most common endocrine malignancy and a variety of studies have examined the incidence of carcinomas in n thyroid disorders. Objective of the present retrospective study was the assessment of the possible influence of age and gender parameters in the presence of thyroid carcinoma in a patient who underwent total thyroidectomy.Material and methods: We studied 107 patients (96 females/11 males) underwent total ...

Background: Medullary thyroid carcinoma (MTC) is characterised by a high concentration of serum calcitonin. Routine measurement of serum calcitonin concentration has been advocated for detection of MTC among patients with nodular thyroid diseases. The aims of our study were to identify medullary thyroid cancer (MTC) in its earliest stages by screening patients with basal calcitonin measurements and to determine whether basal serum calcitonin measurements should be a part of ou...

Introduction: A thyroid nodule discovered in a patient with Graves’ disease (GD) should be evaluated and managed according to guidelines. A subcentimetre incidental thyroid cancer founded in a patients with GD, without high-risk history, without suspicious sonographic (US) features has not been reported yet.Clinical case: A 40-year-old female patient, presented to our hospital with symptoms of thyrotoxicosis. On physical examination heart rate was 1...

Introduction: Metformin-associated lactic acidosis (MALA) is defined as a high anion gap metabolic acidosis with high circulating lactate levels and without hypoperfusion. It is associated with a mortality rate up to 50%.The reported frequency is 0.01–0.05/1000 patient-years, mostly in patients with predisposing factors (which affect its clearance or energy metabolism) such as altered renal function, congestive heart, hepatic and respiratory failure, concomitant medicatio...

Introduction: Drug-induced lupus erythematosus (DILE) is a variant of systemic lupus erythematosus that resolves within days to months after withdrawal of the drug, in a patient with no previous history of SLE.Case report: A 60-year-old female presented at Mother Teresa Hospital with toxic multinodular goiter. She received treatment with propylthiouracil and atenolol for a month, and she developed symptoms like malaise, muscle pain, shortness of breath, ...

Introduction: Thrombosis of the portal venous system is rare with the prevalence about 1% in the general population reported previously, difficult to diagnose and can be fatal. We report a case of previously-undiagnosed type 2 diabetes mellitus presenting as portal venous system thrombosis and reviewed the pertinent medical literature.Case presentation: A 54-year-old white female was admitted to our hospital with 10 days history of vague...

Introduction: Hypothyroidism can cause various degrees of muscular disorders. It can lead to symptoms such as myalgia, weakness, fatigue and in rare cases to extreme muscular damage such as rhabdomyolysis, a potential life-threatening complication. We present the case of a 53 years old patient with acute renal failure due to rhabdomyolysis from severe hypothyroidism.Case description: The patient, a male from Albania was first admitted to the Emergency Ro...

Introduction: The prevalence of thyroid cancer is increasing worldwide as well as in Albania. For the first time we have created the National Thyroid Cancer Register, including the period 2000–2005.Aim: Define the prevalence of thyroid cancer in Albanian population, the prevalence of different histopathologic forms of cancer and the probable risk factors.Results: During this period 83 patients were diagnosed of Thyroid cancer....

Introduction: Subacute thyroiditis-SAT is an acute inflammatory disease of thyroid. It is presumed to be caused by viral infection or a postviral inflammatory process. Whatever factors initiate subacute thyroiditis, the resulting thyroid inflammation damages thyroid follicles and activates proteolysis of the thyroglobulin stored within the follicles. Papillary thyroid carcinoma typically presents as a thyroid nodule. Thyroid nodules come to clinical attention when noted by the...